6-(4-Aminophenyl)-2-ethoxy-4-(2-thienyl)nicotinonitrile

4 - Chloro - 6 - ethoxy - 2 - ( methylthio ) pyrimidine

4,6-Dichloro-2-(methylthio)pyrimidine (3) reacts with EtONa in EtOH, at ca. 20 ◦C, for 2 h, to give exclusively 4-chloro-6-ethoxy-2-(methylthio)pyrimidine (5) in 89% yield. The latter is presented as a useful multifunctionalised pyrimidine scaffold.

Green synthesis and evaluation of 5-(4-aminophenyl)-4-aryl-4H-1, 2, 4-triazole-3-thiol derivatives

The green synthesis of 5-(4-aminophenyl)-4-aryl-4H-1,2,4-triazole-3-thiol was achieved in four steps, In first step, 4-amino benzoic acid refluxed in ethanol along with catalyst Conc. Sulphuric acid to produce ethyl-4-amino benzoate I. Further compound I refluxed with hydrazine hydrate in ethanol to produce 4-amino benzohydrazide II. Compound II refluxed in ethanolic potassium hydroxide with ca...

8 6 4 2

4-(2-{2-[2-(2-Nitro-1H-imidazol-1-yl)ethoxy]eth­oxy}eth­oxy)benzaldehyde

In the mol-ecule of the title compound, C(16)H(19)N(3)O(6), the imidazole ring is essentially planar [maximum deviation = 0.002 (2) Å] and forms a dihedral angle of 5.08 (14)° with the nitro group. In the crystal structure, adjacent mol-ecules are connected via inter-molecular C-H⋯O hydrogen bonds into columns parallel to the a axis.

2-(4-Chloro­phen­yl)-6-meth­oxy­chroman-4-one

In the title mol-ecule, C(16)H(13)Cl O(3), the two aromatic rings form a dihedral angle of 65.3 (1)°. In the crystal structure, weak inter-molecular C-H⋯O hydrogen bonds link the mol-ecules into centrosymmetric dimers, which are further packed into columns propagating in [100] by weak C-H⋯π inter-actions.